Lincomycin and Clindamycin Colitis
نویسندگان
چکیده
منابع مشابه
Effect of clindamycin and lincomycin therapy on faecal flora.
Bacterial counts were carried out on the faeces of 160 patients receiving clindamycin or lincomycin treatment for bacterial infections. In all the patients the total bacteroides count was significantly reduced while strains of Enterobacteriaciae, yeasts, and streptococci were correspondingly increased. Severe diarrhoea developed in 25 (16%) patients, but this could not be related to a change in...
متن کاملIn-vitro comparison of erythromycin, lincomycin, and clindamycin.
The in-vitro antibacterial activities of erythromycin, lincomycin, and clindamycin, a new derivative of lincomycin, were compared. Clindamycin was always more active than lincomycin, and was either as active as erythromycin or more so against betahaemolytic streptococci, Streptococcus viridans, Str. pneumoniae, and erythromycin-sensitive Staphylococcus aureus. It was also fully active against m...
متن کاملSusceptibility of various serogroups of streptococci to clindamycin and lincomycin.
The minimal inhibitory concentration of lincomycin and clindamycin for a large number of strains from multiple serogroups of streptococci was determined. The median minimal inhibitory concentration for streptococci from groups A, B, C, F, G, H, L, and M and nongroupable organisms ranged from 0.02 to 0.39 mug of lincomycin per ml and from </=0.01 to 0.09 mug of clindamycin per ml. Among the grou...
متن کاملEffect of lincomycin and clindamycin on peptide chain initiation.
Lincomycin does not affect initiation factor-dependent formation of 70S initiation complexes formed with fmet-tRNA(F), the initiation triplet A-U-G, and 70S ribosomes, whereas its 7-chloro-derivative clindamycin substantially stimulates this process. Conversely, lincomycin stimulates nonenzymatic formation of the 70S complex, but clindamycin does not. Both antibiotics stimulate the assembly of ...
متن کاملThe effect of clindamycin and lincomycin on angiogenic activity of human blood mononuclear cells
Antibiotics are used in clinical practice very frequently. One should realize, however, that antibiotic therapy may deeply influence human organism changing its homeostasis. It may concern many important processes including host inflammatory and immune response [1]. Clindamycin and lincomycin belong to lincosamides with chemical structure consisting of amino acid and sugar moieties. Their antim...
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ژورنال
عنوان ژورنال: BMJ
سال: 1974
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.4.5939.289